Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 6/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858320 | 0.92 | CASP2 (0.61) | EPHX2FAAHNOD1CASP2 | |
| SCHEMBL8858327 | 0.91 | CASP2 (0.59) | EPHX2KDM4EFAAHNOD1CASP2 | |
| SCHEMBL6238522 | 0.91 | CASP2 (0.59) | EPHX2KDM4EFAAHNOD1CASP2 | |
| SCHEMBL498119 | 0.89 | FAAH (0.56) | EPHX2FAAHNOD1CNR1CNR2 | |
| SCHEMBL8958476 | 0.89 | FAAH (0.56) | EPHX2FAAHNOD1CNR1CNR2 | |
| SCHEMBL8958634 | 0.89 | FAAH (0.56) | EPHX2FAAHNOD1CNR1CNR2 | |
| SCHEMBL8958626 | 0.89 | FAAH (0.56) | EPHX2FAAHNOD1CNR1CNR2 | |
| SCHEMBL8958606 | 0.89 | FAAH (0.56) | EPHX2FAAHNOD1CNR1CNR2 | |
| Dodecanoate SCHEMBL28870307 | 0.87 | EPHX2 (0.76) | EPHX2KDM4EFAAHFFAR4FFAR1 | |
| SCHEMBL8858321 | 0.87 | CASP2 (0.57) | EPHX2KDM4EFAAHNOD1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916521-B2 | Cleaning medium for magnetic recording apparatus | FUJI PHOTO FILM CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |