Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298870 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL6300004 | 0.90 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL6300006 | 0.90 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL6298878 | 0.77 | HPGD (0.43) | ALDH1A1LMNACYP3A4TSHRPPARG | |
| SCHEMBL6298881 | 0.77 | HPGD (0.43) | ALDH1A1LMNACYP3A4TSHRPPARG | |
| SCHEMBL2804053 | 0.76 | TDP1 (0.46) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL14114272 | 0.76 | TDP1 (0.38) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL2764142 | 0.74 | TDP1 (0.37) | ALDH1A1MAPK1CA2TDP1PTPN1 | |
| SCHEMBL680571 | 0.74 | TDP1 (0.37) | ALDH1A1MAPK1CA2TDP1PTPN1 | |
| SCHEMBL7475244 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875895-B2 | Such as 1,4-bis(2-(4-bromophenyl)-2-phenylethenyl)-2-(2-ethylhexyloxy)-5 -methoxybenzene; for polymerization into a light-emitting material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-05-29 | — | — | US | disclosed |
| EP-1288184-A1 | Bis(diphenylvinyl)arene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100786-A1 | Bis (diphenylvinyl) arene compound | CBR1, AR, CYP1B1 | ALDH1A1 266/4885LMNA 3278/4885MAPK1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.