Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680571 | 1.00 | TDP1 (0.37) | TDP1HTR2APTPN1TAAR1PRKDC | |
| SCHEMBL7645902 | 0.88 | HTR2A (0.43) | TDP1HTR2ATAAR1ALDH1A1MAPK1 | |
| SCHEMBL4582176 | 0.87 | TNFRSF1A (0.32) | TDP1HTR2APTPN1TAAR1PRKDC | |
| SCHEMBL2804053 | 0.83 | TDP1 (0.46) | TDP1ALDH1A1MAPK1CA2 | |
| SCHEMBL2053675 | 0.82 | CYP3A4 (0.43) | TDP1ALDH1A1MAPK1CA2 | |
| SCHEMBL2037739 | 0.82 | LMNA (0.46) | TDP1PRKDCALDH1A1MAPK1CA2 | |
| SCHEMBL7475244 | 0.82 | ALDH1A1 (0.47) | TDP1PRKDCALDH1A1MAPK1CA2 | |
| SCHEMBL6846661 | 0.81 | APP (0.50) | TDP1MAPK1 | |
| SCHEMBL17776459 | 0.81 | TDP1 (0.37) | TDP1PTPN1ALDH1A1MAPK1CA2 | |
| SCHEMBL28083440 | 0.79 | CYP3A4 (0.43) | TDP1ALDH1A1MAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915788-B1 | SOLVENT MIXTURES FOR ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| EP-1915788-A1 | SOLVENT MIXTURE FOR ORGANIC SEMICONDUCTORS | Merck Patent GmbH (DE) | 2008-04-30 | — | — | EP | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
| WO-2007019944-A1 | SOLVENT MIXTURE FOR ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |
| EP-1427768-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2007-01-24 | — | — | EP | disclosed |
| EP-1656408-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| US-20050038223-A1 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| WO-2005014689-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |
| EP-1427768-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003020790-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | ALDH1A2, SELE, PPOX | TDP1 3961/4885HTR2A 4207/4885PTPN1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.