⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303845 | 0.97 | — | — | |
| SCHEMBL7574241 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL3650320 | 0.72 | TSHR (0.40) | — | |
| SCHEMBL59739 | 0.67 | TSHR (0.53) | — | |
| SCHEMBL1324284 | 0.67 | FAAH (0.68) | — | |
| SCHEMBL29274398 | 0.67 | FAAH (0.68) | — | |
| SCHEMBL819092 | 0.67 | FAAH (0.68) | — | |
| SCHEMBL506356 | 0.67 | FAAH (0.68) | — | |
| SCHEMBL28251383 | 0.66 | TSHR (0.73) | — | |
| Octane SCHEMBL27804363 | 0.66 | TSHR (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143453-A1 | Selective preventing and therapeutic agents for progressive lesion after organic damage | ISHIBASHI MICHIO (JP) | 2005-06-30 | — | — | US | disclosed |
| US-6878745-B2 | Selective preventives/remedies for progressive lesions after organ damage | Ishibashi, Michio (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20030181506-A1 | Selective preventives/remedies for progressive lesions after organ damage | ISHIBASHI, MICHIO (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1277747-A1 | SELECTIVE PREVENTIVES/REMEDIES FOR PROGRESSIVE LESIONS AFTER ORGAN DAMAGE | Ishibashi, Michio (JP) | 2003-01-22 | — | — | EP | disclosed |