SCHEMBL6299090

SCHEMBL6299090

c1csc(-c2c3ccccc3cc3ccccc23)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.49
RPS6KB2 Q9UBS0 2/20 0.48
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 5/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
HSD17B10 Q99714 1/20 0.43
NQO2 P16083 2/20 0.42
ATM Q13315 1/20 0.42
ADORA2A P29274 1/20 0.42
HPGD P15428 6/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
BLM P54132 1/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14195766 0.91 ACHE (0.43) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL27893392 0.88 RPS6KB2 (0.44) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL16080111 0.87 DPP4 (0.45) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL29361026 0.85 RPS6KB2 (0.55) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL4857297 0.85 RPS6KB2 (0.55) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL13130593 0.84 ACHE (0.56) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL29658035 0.84 ACHE (0.56) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL28314838 0.83 ACHE (0.40) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL17197708 0.82 ACHE (0.42) ACHERPS6KB2ALDH1A1KDM4ERAB9A
SCHEMBL15853290 0.79 NQO2 (0.43) ACHERPS6KB2ALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303860-A Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2020-06-19 CN claimed
US-20150299437-A1 PREPARATION OF RUBBER REINFORCED WITH GRAPHENE AND CARBON NANOTUBES AND FUNCTIONALIZED ELASTOMERS AND TIRE WITH COMPONENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-10-22 US claimed
US-20220326613-A1 PHOTOSENSITIVE TRANSFER MATERIAL AND METHOD OF PRODUCING THE SAME, METHOD OF PRODUCING PATTERNED METAL CONDUCTIVE MATERIAL, FILM, TOUCH PANEL, METHOD OF SUPPRESSING DETERIORATION, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-10-13 US disclosed
CN-111303860-B Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2021-05-14 CN disclosed
CN-111303860-A Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2020-06-19 CN disclosed
US-20150299437-A1 PREPARATION OF RUBBER REINFORCED WITH GRAPHENE AND CARBON NANOTUBES AND FUNCTIONALIZED ELASTOMERS AND TIRE WITH COMPONENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-10-22 US disclosed
CN-102464978-B Conductive cavity-type blue electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2014-06-11 CN disclosed
CN-102464650-B Organic semiconductor material containing anthracene, thiofuran and truxene and preparation method and application of organic semiconductor material OCEANS KING LIGHTING SCIENCE 2013-10-09 CN disclosed
CN-102464978-A Conductive cavity-type blue electroluminescent material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2012-05-23 CN disclosed
CN-102464650-A Organic semiconductor material containing anthracene, thiofuran and truxene and preparation method and application of organic semiconductor material OCEANS KING LIGHTING SCIENCE 2012-05-23 CN disclosed
US-6916931-B2 Tridentate ligands and relative complexes with transition metals POLIMERI EUROPA S.P.A. (IT) 2005-07-12 US disclosed
US-20040087788-A1 Tridentate ligands and relative complexes with transition metals POLIMERI EUROPA S.P.A. (IT) 2004-05-06 US disclosed
EP-1334101-B1 TRIDENTATE LIGANDS AND RELATIVE COMPLEXES WITH TRANSITION METALS POLIMERI EUROPA SPA (IT) 2004-04-28 EP disclosed
EP-1334101-A2 TRIDENTATE LIGANDS AND RELATIVE COMPLEXES WITH TRANSITION METALS Polimeri Europa S.p.A. (IT) 2003-08-13 EP disclosed
WO-2002034746-A2 TRIDENTATE LIGANDS AND RELATIVE COMPLEXES WITH TRANSITION METALS POLIMERI EUROPA S.P.A. (IT) 2002-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087788-A1 Tridentate ligands and relative complexes with transition metals TFRC, TCP1, CCR6 ACHE 4728/4885RPS6KB2 3868/4885ALDH1A1 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.