Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635387 | 0.92 | LMNA (0.43) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL5987683 | 0.90 | TSHR (0.46) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL5987635 | 0.90 | TSHR (0.46) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL7603104 | 0.90 | TSHR (0.46) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL27743278 | 0.89 | CYP2C19 (0.38) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL10293909 | 0.88 | CYP2C19 (0.35) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL13647279 | 0.88 | MMP1 (0.50) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL18331644 | 0.88 | CYP2C19 (0.35) | CYP2C19MEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL3836321 | 0.88 | LMNA (0.55) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL26669062 | 0.88 | MEN1 (0.35) | CYP2C19MEN1RECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115282913-A | Reaction system and method for preparing methyl propionate | 中国海洋石油集团有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-6902785-B2 | Laminar structure | DENOVUS LLC (US) | 2005-06-07 | — | — | US | disclosed |
| US-6638590-B2 | Tacky mastic in contact with ultraviolet light and moisture barrier; for protection of wood, metal, concrete, cement | DENOVUS LLC | 2003-10-28 | — | — | US | disclosed |
| EP-0219906-B1 | PROCESS FOR THE PREPARATION OF ALKYLIDENE DIESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-06 | — | — | EP | disclosed |
| US-4810821-A | CATALYTIC CARBONYLATION, HYDROGENATION, ESTERIFICATION | MONSANTO COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0219906-A2 | Process for the preparation of alkylidene diesters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-29 | — | — | EP | disclosed |
| EP-0077116-B1 | PREPARATION OF ALKYLIDENE DIESTERS | MONSANTO COMPANY (US) | 1984-09-12 | — | — | EP | disclosed |
| EP-0077116-A1 | Preparation of alkylidene diesters | MONSANTO COMPANY (US) | 1983-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318922-A1 | Bicyclic Pyrrole Derivatives | DPP4, DPP7, DPP3 | CYP2C19 41/4885MEN1 3498/4885RECQL 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.