⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306865 | 0.77 | — | — | |
| SCHEMBL3846079 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL5125916 | 0.73 | — | — | |
| SCHEMBL28872389 | 0.73 | — | — | |
| SCHEMBL1418811 | 0.73 | — | — | |
| SCHEMBL5675515 | 0.72 | MAOB (0.44) | — | |
| SCHEMBL15067834 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL15067836 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL8000880 | 0.72 | — | — | |
| SCHEMBL5675512 | 0.72 | MAOB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279802-B | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2024-04-12 | — | — | CN | claimed |
| CN-115279802-A | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2022-11-01 | — | — | CN | claimed |
| CN-115279802-B | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2024-04-12 | — | — | CN | disclosed |
| CN-115279802-A | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2022-11-01 | — | — | CN | disclosed |
| WO-2016145614-A1 | TRIAZOLYL PYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-22 | — | — | WO | disclosed |
| US-6911469-B2 | Sulfonamide compounds and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| US-20020099212-A1 | For therapy of disease treatable based on a blood sugar level-depressing activity or a disease treatable based on a cGMP-PDE inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-07-25 | — | — | US | disclosed |
| US-6348474-B1 | COMPOUNDS AS ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| CN-1268942-A | Sulfonamide compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| EP-0995742-A1 | SULFONAMIDE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-26 | — | — | EP | disclosed |