Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295691 | 0.87 | TUBB4A (0.55) | MAP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6295739 | 0.86 | ALOX5 (0.58) | MAP2POLBTUBB4ATUBBTUBA3C | |
| SCHEMBL6295963 | 0.84 | MAP2 (0.47) | MAP2PDE10ACA1CA2MEN1 | |
| SCHEMBL6295994 | 0.82 | MAP2 (0.45) | MAP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6300664 | 0.81 | PDE10A (0.60) | MAP2PDE10ACA1CA2MEN1 | |
| SCHEMBL6300802 | 0.80 | ABCG2 (0.54) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6294965 | 0.80 | SERPINE1 (0.49) | MAP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25199917 | 0.78 | KDM4E (0.42) | MAP2PDE10ACA1CA2MEN1 | |
| SCHEMBL6295661 | 0.77 | MAP2 (0.52) | MAP2MAPK1PDE10ACA1CA2 | |
| SCHEMBL6295986 | 0.75 | KDM4E (0.51) | MAP2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897316-B2 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-05-24 | — | — | US | disclosed |
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHUK | MAP2 518/4885POLB 1876/4885TUBB4A 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.