Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211084 | 0.90 | CCR2 (0.81) | CCR2ABCB11PTGS2 | |
| SCHEMBL6307986 | 0.86 | CCR2 (0.76) | CCR2ABCB11PTGS2 | |
| SCHEMBL2924383 | 0.86 | CCR2 (0.76) | CCR2ABCB11PTGS2 | |
| SCHEMBL6306929 | 0.84 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6303108 | 0.83 | CCR2 (0.79) | CCR2ABCB11 | |
| SCHEMBL4366544 | 0.83 | CCR2 (0.71) | CCR2ABCB11PTGS2 | |
| SCHEMBL6307747 | 0.82 | CCR2 (0.81) | CCR2ABCB11 | |
| SCHEMBL6592482 | 0.82 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6303320 | 0.81 | CCR2 (0.80) | CCR2ABCB11 | |
| SCHEMBL6300817 | 0.81 | CCR2 (0.76) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953809-B2 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | disclosed |
| US-20030119830-A1 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED | 2003-06-26 | — | — | US | disclosed |
| US-6441004-B1 | INDOLE DERIVATIVES AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 2002-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119830-A1 | Monocyte chemoattractant protein-1 inhibitor compounds | CCL2, CCL11, CCR1 | CCR2 4/4885ABCB11 506/4885PTGS2 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.