Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296403 | 0.75 | ACHE (0.59) | ACHECYP19A1CES1 | |
| SCHEMBL29752636 | 0.75 | ACHE (0.59) | ACHECYP19A1CES1 | |
| SCHEMBL1923692 | 0.73 | IDO1 (0.46) | ANPEPIDO1CA1CA2PLAU | |
| SCHEMBL31490422 | 0.73 | IDO1 (0.46) | ANPEPIDO1CA1CA2PLAU | |
| SCHEMBL11822112 | 0.72 | HTR2A (0.57) | ANPEP | |
| SCHEMBL1170559 | 0.72 | — | — | |
| SCHEMBL3345089 | 0.70 | MAOB (0.43) | CYP1A2ACHECYP19A1 | |
| SCHEMBL2485525 | 0.70 | IDO1 (0.44) | CYP1A2ANPEPIDO1ACHECA1 | |
| SCHEMBL13866808 | 0.70 | IDO1 (0.44) | CYP1A2ANPEPIDO1ACHECA1 | |
| SCHEMBL6317426 | 0.70 | IDO1 (0.44) | CYP1A2ANPEPIDO1ACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1268429-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001079172-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER Departament Brevets/Fontanes (FR) | 2001-10-25 | — | — | WO | disclosed |