Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.59 |
| ▸ | METAP1 | P53582 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29752636 | 1.00 | ACHE (0.59) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL29604926 | 0.79 | CYP19A1 (0.51) | ACHECYP19A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL3346153 | 0.79 | CYP19A1 (0.51) | ACHECYP19A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL10983987 | 0.78 | S100A4 (0.59) | ACHECYP19A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14157895 | 0.77 | ACHE (0.63) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL5539639 | 0.77 | ACHE (0.63) | ACHEMETAP1CYP19A1TSHRSMN1; SMN2 | |
| SCHEMBL2592601 | 0.76 | MAOA (0.50) | ACHECYP19A1TSHRKDM4EMAPT | |
| SCHEMBL11776080 | 0.76 | ACHE (0.61) | ACHEMETAP1CYP19A1TSHRKDM4E | |
| SCHEMBL7178718 | 0.76 | TYRO3 (0.49) | ACHESMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL6206085 | 0.76 | TDP2 (0.47) | SMN1; SMN2KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010613-A1 | NOVEL SYNTHETIC PATHWAY TO BELZUTIFAN | MERCK SHARP & DOHME LLC (US) | 2024-01-11 | — | — | US | claimed |
| WO-2021038581-A1 | A ONE STEP SYNTHESIS OF 2-SUBSTITUTED BENZO[B]THIOPHENES | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT Madras) (IN) | 2021-03-04 | — | — | WO | claimed |
| EP-1934241-B1 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL SCIENT IND RES (IN) | 2012-11-14 | — | — | EP | claimed |
| US-20090137541-A1 | Novel Series of Imidazolyl Substituted Steroidal and Indan-1-One Derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-05-28 | — | — | US | claimed |
| EP-1934241-A2 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007031833-A2 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | claimed |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| US-20240368001-A1 | SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF | AQUAFORTUS TECHNOLOGIES LIMITED (NZ) | 2024-11-07 | — | — | US | disclosed |
| US-11987506-B2 | Salt recovery solution and processes of use thereof | AQUAFORTUS TECHNOLOGIES LIMITED (NZ) | 2024-05-21 | — | — | US | disclosed |
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | VERNALIS (R&D) LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| CN-114685518-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| US-4616013-A | INOTROPIC AND VASODILATOR ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-10-07 | — | — | US | disclosed |
| EP-0189472-A1 | PYRIMIDINONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001205-A1 | PYRIMIDINONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1986-02-27 | — | — | WO | disclosed |
| EP-0145236-A2 | Thiadiazinone compounds, process for their preparation, and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-19 | — | — | EP | disclosed |
| US-4174397-A | TREATMENT OF OBESITY AND LIPID METABOLISM DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-3954983-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3932430-A | Substituted indeno, naphtho and cyclohepta pyrazoles | SANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BAX, BCL2A1 | ACHE 4262/4885METAP1 4494/4885CYP19A1 576/4885 |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BCL2A1, BAX | ACHE 4801/4885METAP1 3656/4885CYP19A1 1947/4885 |
| US-20240010613-A1 | NOVEL SYNTHETIC PATHWAY TO BELZUTIFAN | HIF1AN, VHL, HIF1A | ACHE 4885/4885METAP1 4381/4885CYP19A1 1293/4885 |
| US-20090137541-A1 | Novel Series of Imidazolyl Substituted Steroidal and Indan-1-One Derivatives | NR5A1, NR3C2, CYP17A1 | ACHE 3737/4885METAP1 4184/4885CYP19A1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.