Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7155325 | 0.96 | F2 (0.47) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6294700 | 0.93 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6294964 | 0.92 | F2 (0.48) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7151193 | 0.90 | PRSS1 (0.51) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7154778 | 0.89 | PLA2G7 (0.46) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL7155329 | 0.89 | F2 (0.47) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.89 | F2 (0.48) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6295817 | 0.84 | PLA2G7 (0.46) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7158701 | 0.84 | F2 (0.53) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6295821 | 0.84 | PLA2G7 (0.44) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |