Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7158701

N=C(N)c1ccc2cc(Oc3ccc(NS(=O)(=O)c4ccc(F)cc4)cc3C(=O)O)ccc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2 P00734 10/20 0.53
PRSS1 P07477 3/20 0.53
PRSS2 P07478 3/20 0.53
PRSS3 P35030 3/20 0.53
ST14 Q9Y5Y6 3/20 0.53
MRGPRX1 Q96LB2 1/20 0.48
PLA2G7 Q13093 3/20 0.45
F10 P00742 4/20 0.44
F3 P13726 12/20 0.44
F7 P08709 3/20 0.44
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7154050 0.93 F2 (0.53) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7151221 0.93 ST14 (0.62) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7153927 0.92 F2 (0.49) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7150780 0.91 PRSS1 (0.55) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7158302 0.90 F2 (0.59) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7157181 0.90 F3 (0.50) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7158713 0.90 F2 (0.48) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL7155325 0.89 F2 (0.47) F2PRSS1PRSS2PRSS3ST14
Trifluoroacetic Acid SCHEMBL6300672 0.87 F10 (0.48) F2F10F3F7
Trifluoroacetic Acid SCHEMBL7150667 0.86 PGR (0.48) F2PRSS1PRSS2PRSS3ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1312602-A1 Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them Eisai Co., Ltd. (JP) 2003-05-21 EP disclosed