Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300621 | 0.90 | CCR2 (0.81) | CCR2ABCB11 | |
| SCHEMBL6300905 | 0.89 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6308083 | 0.86 | CCR2 (0.81) | CCR2ABCB11 | |
| SCHEMBL6301048 | 0.85 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6303301 | 0.85 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6303484 | 0.84 | CCR2 (0.72) | CCR2ABCB11 | |
| SCHEMBL6302521 | 0.83 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL7080358 | 0.82 | CCR2 (0.70) | CCR2ABCB11 | |
| SCHEMBL6308101 | 0.82 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL6303492 | 0.82 | CCR2 (0.74) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953809-B2 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED (GB) | 2005-10-11 | — | — | US | claimed |
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | claimed |
| US-20030119830-A1 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED | 2003-06-26 | — | — | US | claimed |
| EP-1003504-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | AstraZeneca UK Limited (GB) | 2000-05-31 | — | — | EP | claimed |
| WO-1999007351-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | claimed |
| WO-2025003769-A2 | AROMATIC HETEROCYCLIC PYRROLIDONE DERIVATIVE AND USE THEREOF | 杭州百新生物医药科技有限公司 | 2025-01-02 | — | — | WO | disclosed |
| US-6953809-B2 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |
| EP-1097118-B1 | ALKYLATION PROCESS | ALBEMARLE CORP (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | disclosed |
| US-20030119830-A1 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED | 2003-06-26 | — | — | US | disclosed |
| US-6441004-B1 | INDOLE DERIVATIVES AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 2002-08-27 | — | — | US | disclosed |
| EP-1097118-A1 | ALKYLATION PROCESS | ALBEMARLE CORPORATION (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6100437-A | ALKYLATION IS CARRIED OUT AT A LOWER TEMPERATURE AND A MIXED SODIUM-POTASSIUM CATALYST IS USED AT A HIGHER CONCENTRATION THAN HERETOFORE; INSOLUBLE TAR IS VISUALLY UNDETECTABLE, AND THE PRESENCE OF COLORED SOLUBLE BYPRODUCTS IS REDUCED | ALBEMARLE CORPORATION (US) | 2000-08-08 | — | — | US | disclosed |
| EP-1003504-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | AstraZeneca UK Limited (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-2000002835-A1 | ALKYLATION PROCESS | ALBEMARLE CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999007351-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119830-A1 | Monocyte chemoattractant protein-1 inhibitor compounds | CCL2, CCL11, CCR1 | CCR2 4/4885ABCB11 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.