Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308147 | 0.88 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL4576392 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL13943912 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8724654 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8070399 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL6725774 | 0.82 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6732850 | 0.82 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL4575048 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8068392 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL2126159 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869968-B1 | Such as 3-(4-fluorophenyl)-4-(4-methysulphonylphenyl)-2-(3H)-oxazolone; for treating colorectal cancer, fevers, and inflammation | ALLMIRALL PRODESFARMA S.A. (ES) | 2005-03-22 | — | — | US | claimed |
| EP-0888316-B1 | 2-(3H)-OXAZOLONE DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS | ALMIRALL PRODESFARMA SA (ES) | 2000-11-02 | — | — | EP | claimed |
| WO-1998011080-A1 | NOVEL 3,4-DIARYLOXAZOLONE DERIVATIVES, METHODS OF PREPARATION AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-03-19 | — | — | WO | claimed |
| US-6869968-B1 | Such as 3-(4-fluorophenyl)-4-(4-methysulphonylphenyl)-2-(3H)-oxazolone; for treating colorectal cancer, fevers, and inflammation | ALLMIRALL PRODESFARMA S.A. (ES) | 2005-03-22 | — | — | US | disclosed |
| EP-0888316-B1 | 2-(3H)-OXAZOLONE DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS | ALMIRALL PRODESFARMA SA (ES) | 2000-11-02 | — | — | EP | disclosed |
| EP-0888316-A1 | 2-(3H)-OXAZOLONE DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS | ALMIRALL-PRODESFARMA, S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1998011080-A1 | NOVEL 3,4-DIARYLOXAZOLONE DERIVATIVES, METHODS OF PREPARATION AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997034882-A1 | 2-(3H)-OXAZOLONE DERIVATIVES AND THEIR USE AS COX-2 INHIBITORS | ALMIRALL PRODESFARMA, S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |