Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842608 | 0.92 | KDM4E (0.43) | ACHEKEAP1NFE2L2SLC6A5L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4841723 | 0.91 | KDM4E (0.42) | ACHEKEAP1NFE2L2SLC6A5L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4832567 | 0.91 | KDM4E (0.42) | ACHEKEAP1NFE2L2SLC6A5L3MBTL1 | |
| SCHEMBL4832702 | 0.81 | GAA (0.41) | ACHEKEAP1NFE2L2GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4832297 | 0.81 | F10 (0.50) | L3MBTL1L3MBTL3KDM4EALDH1A1 | |
| SCHEMBL6379660 | 0.80 | ACHE (0.48) | ACHESLC6A5GAAGPR119L3MBTL1 | |
| SCHEMBL4840253 | 0.78 | KDM4E (0.45) | ACHEL3MBTL1L3MBTL3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4841921 | 0.78 | KDM4E (0.44) | ACHEKEAP1NFE2L2L3MBTL1L3MBTL3 | |
| SCHEMBL4832817 | 0.77 | ALDH1A1 (0.44) | ACHEL3MBTL1L3MBTL3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4840498 | 0.76 | ALDH1A1 (0.43) | ACHEL3MBTL1L3MBTL3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936611-B2 | Serine protease inhibitors | ELI LILLY AND COMPANY (US) | 2005-08-30 | — | — | US | claimed |