Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 10/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 4/20 | 0.51 |
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | VDR | P11473 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133868 | 1.00 | NPC1L1 (0.55) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL6303110 | 1.00 | NPC1L1 (0.55) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL6300889 | 1.00 | NPC1L1 (0.55) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL16163620 | 1.00 | NPC1L1 (0.55) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL26121912 | 0.90 | NPC1L1 (0.53) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL26979040 | 0.90 | NPC1L1 (0.53) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL26121915 | 0.90 | NPC1L1 (0.53) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL16163667 | 0.90 | USP2 (0.50) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL14976644 | 0.90 | USP2 (0.50) | NPC1L1USP2LMNAMEN1TP53 | |
| Acetic Acid SCHEMBL9580320 | 0.89 | NPC1L1 (0.65) | NPC1L1USP2LMNAMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841665-B2 | Method for synthesizing 5β, 6β-epoxides of steroids by a highly β-selective epoxidation of ΔΔ5-unsaturated steroids catalyzed by ketones | THE UNIVERSITY OF HONG KONG (CN) | 2005-01-11 | — | — | US | disclosed |
| WO-2003074545-A1 | METHOD FOR SYNTHESIZING 5ß, 6ß-EPOXIDES OF STEROIDS BY A HIGHLY ß-SELECTIVE EPOXIDATION OF Δ5-UNSATURATED STEROIDS CATALYZED BY KETONES | THE UNIVERSITY OF HONG KONG (CN) | 2003-09-12 | — | — | WO | disclosed |
| US-20030018188-A1 | Method for synthesizing 5beta, 6beta-epoxides of steroids by a highly beta-selective epoxidation of delta5-unsaturated steroids catalyzed by ketones | UNIVERSITY OF HONG KONG, THE (HK) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018188-A1 | Method for synthesizing 5beta, 6beta-epoxides of steroids by a highly beta-selective epoxidation of delta5-unsaturated steroids catalyzed by ketones | SRD5A2, HSD17B7, SRD5A1 | NPC1L1 2149/4885USP2 1794/4885LMNA 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.