Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304019 | 0.90 | ALDH1A1 (0.54) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6303586 | 0.85 | PPARG (0.56) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7652168 | 0.85 | PPARG (0.54) | PPARGALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL6173254 | 0.84 | PPARG (0.62) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6301170 | 0.83 | PPARG (0.52) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6308856 | 0.83 | PPARG (0.52) | PPARGALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL7654594 | 0.83 | PPARG (0.52) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6307898 | 0.82 | PPARG (0.51) | PPARGALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL6303281 | 0.82 | PPARG (0.51) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6304484 | 0.82 | PPARG (0.51) | PPARGALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |