Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301230 | 0.90 | PPARG (0.51) | ALDH1A1MAPTSMN1; SMN2PPARGHPGD | |
| SCHEMBL7651458 | 0.85 | PPARG (0.56) | ALDH1A1MAPTSMN1; SMN2PPARGHSD17B10 | |
| SCHEMBL6308437 | 0.84 | PPARG (0.78) | ALDH1A1MAPTSMN1; SMN2PPARGHPGD | |
| SCHEMBL6301588 | 0.84 | PPARG (0.57) | ALDH1A1MAPTSMN1; SMN2PPARGHPGD | |
| SCHEMBL6304950 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2PPARGHPGD | |
| SCHEMBL6170044 | 0.82 | PPARG (0.64) | SMN1; SMN2PPARGMEN1KMT2ALMNA | |
| SCHEMBL6309647 | 0.81 | PPARG (0.54) | PPARG | |
| SCHEMBL7660647 | 0.80 | PPARG (0.56) | ALDH1A1MAPTSMN1; SMN2PPARG | |
| SCHEMBL6309778 | 0.80 | PPARG (0.52) | ALDH1A1MAPTSMN1; SMN2PPARGKDM4E | |
| SCHEMBL7656331 | 0.80 | PPARG (0.52) | ALDH1A1MAPTSMN1; SMN2PPARGHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |