Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.59 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 4/20 | 0.39 |
| ▸ | ARG1 | P05089 | 3/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL3677532 | 1.00 | GSR (0.59) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Lysine SCHEMBL27944317 | 1.00 | GSR (0.59) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Lysine SCHEMBL1042959 | 1.00 | GSR (0.59) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Lysine SCHEMBL6301386 | 1.00 | GSR (0.59) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Lysine SCHEMBL9574568 | 0.99 | GSR (0.57) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Lysine SCHEMBL9118672 | 0.87 | GSR (0.61) | GSRPTGS1GSTK1CPB2FOLH1 | |
| Cysteine SCHEMBL28399079 | 0.82 | PTGS1 (0.59) | GSRPTGS1GSTK1FOLH1SLC7A11 | |
| SCHEMBL4158587 | 0.82 | FOLH1 (0.50) | GSRPTGS1GSTK1CPB2FOLH1 | |
| SCHEMBL31448267 | 0.81 | GSR (0.50) | GSRARG2ARG1GRM8GRM6 | |
| SCHEMBL43620 | 0.81 | FOLH1 (0.57) | GSRCPB2FOLH1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117357420-A | Hair care composition, hair care essence and preparation method thereof | 拉芳家化股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-113546000-B | High-stability whitening skin care product and preparation method thereof | 北京美丽臻颜化妆品有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-113546000-A | High-stability whitening skin care product and preparation method thereof | 北京美丽臻颜化妆品有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-117357420-A | Hair care composition, hair care essence and preparation method thereof | 拉芳家化股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-113546000-B | High-stability whitening skin care product and preparation method thereof | 北京美丽臻颜化妆品有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113546000-A | High-stability whitening skin care product and preparation method thereof | 北京美丽臻颜化妆品有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-104010525-B | Cyclohexanol derivative as antibacterial anti-microbial active matter purposes | 默克专利股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-103675280-B | Marker and reagent for detecting HCV core antigen | BIOBASE BIODUSTRY SHANDONG CO | 2015-05-20 | — | — | CN | disclosed |
| CN-103675280-A | Marker and reagent for detecting HCV core antigen | BIOBASE BIODUSTRY SHANDONG CO | 2014-03-26 | — | — | CN | disclosed |
| US-6893631-B1 | Shaving soap and aftershave gel and methods of use thereof | MITCHELL & SONS, LLC (US) | 2005-05-17 | — | — | US | disclosed |