SCHEMBL6301480

SCHEMBL6301480

O=S(=O)(c1ccc(OCc2ccccc2)cc1)c1ccc(OCC2CO2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.76
PKM P14618 2/20 0.76
LMNA P02545 1/20 0.76
GAA P10253 1/20 0.76
TDP1 Q9NUW8 1/20 0.58
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CA4 P22748 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
AR P10275 8/20 0.47
CTRC Q99895 1/20 0.46
TP53 P04637 3/20 0.45
TSHR P16473 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6297248 0.90 ALDH1A1 (0.88) ALDH1A1PKMLMNAGAATDP1
SCHEMBL1351514 0.89 TDP1 (0.73) ALDH1A1PKMLMNAGAATDP1
SCHEMBL3287709 0.89 TDP1 (0.73) ALDH1A1PKMLMNAGAATDP1
SCHEMBL1228699 0.89 TDP1 (0.73) ALDH1A1PKMLMNAGAATDP1
SCHEMBL7693412 0.87 TDP1 (0.71) ALDH1A1PKMLMNAGAATDP1
SCHEMBL313096 0.87 ALDH1A1 (1.00) ALDH1A1PKMLMNAGAATDP1
SCHEMBL6301481 0.87 ALDH1A1 (0.72) ALDH1A1PKMLMNAGAATDP1
SCHEMBL7693411 0.86 TDP1 (0.69) ALDH1A1PKMLMNAGAATDP1
SCHEMBL7108878 0.84 CA12 (0.74) ALDH1A1LMNAGAACA12CA1
SCHEMBL9260073 0.82 CA12 (0.72) LMNAGAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
EP-0618082-B1 A heat-sensitive recording material NICCA CHEMICAL CO (JP) 1998-01-21 EP disclosed
US-5378674-A Heat-sensitive recording material NICCA CHEMICAL CO., LTD. (JP) 1995-01-03 US disclosed
EP-0618082-A1 A heat-sensitive recording material NICCA CHEMICAL CO., Ltd. (JP) 1994-10-05 EP disclosed
EP-0616897-A2 A heat-sensitive recording material NICCA CHEMICAL CO., LTD. (JP) 1994-09-28 EP disclosed
US-5348930-A Leuco dye, developer, sensitizer NICCA CHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
EP-0563392-A1 2-PROPANOL COMPOUND AND RECORDING MATERIAL PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1993-10-06 EP disclosed