SCHEMBL6301557

SCHEMBL6301557

O=C(CC(=O)c1ccc[nH]1)Nc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
RAB9A P51151 2/20 0.49
GAA P10253 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPC1 O15118 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM1A O60341 1/20 0.47
EPHX2 P34913 1/20 0.47
MAPT P10636 2/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4954697 0.79 NPC1 (0.59) RAB9ASMN1; SMN2NPC1KMT2AKDM1A
SCHEMBL28053617 0.77 SMN1; SMN2 (0.63) TSHRRAB9AGAASMN1; SMN2NPC1
SCHEMBL5162800 0.77 TSHR (0.53) TSHRRAB9AGAASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL31228757 0.77 KDM1A (0.60) RAB9ASMN1; SMN2NPC1KMT2AKDM1A
SCHEMBL1689206 0.75 EPHX2 (0.68) TSHRGAASMN1; SMN2KMT2AKDM1A
SCHEMBL9485984 0.75 EPHX2 (0.58) GAAKMT2AEPHX2MAPTHDAC3
SCHEMBL5160575 0.75 TSHR (0.50) TSHRRAB9AGAASMN1; SMN2NPC1
SCHEMBL1098345 0.74 RAB9A (0.77) RAB9AGAASMN1; SMN2NPC1KMT2A
SCHEMBL11572863 0.74 RAB9A (0.71) RAB9ASMN1; SMN2NPC1KMT2AKDM1A
SCHEMBL31203339 0.74 HDAC1 (0.71) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751428-B1 Novel image-dye-forming couplers and photographic elements containing them KODAK LTD (GB) 1999-10-06 EP claimed
US-5674667-A COLORFASTNESS; CONTRAST EASTMAN KODAK COMPANY (US) 1997-10-07 US claimed
EP-0751428-A1 Novel image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP claimed
US-6927020-B2 Silver halide color photographic material KONICA MINOLTA HOLDINGS, INC. (JP) 2005-08-09 US disclosed
US-20040157173-A1 Silver halide color photographic material KONICA MINOLTA HOLDINGS, INC. 2004-08-12 US disclosed
EP-1253469-A1 Photographic element containing imidazolonoylacetanilide coupler EASTMAN KODAK COMPANY (US) 2002-10-30 EP disclosed
US-6455241-B1 ELEMENT EXHIBITS IMPROVED DYE-FORMING ACTIVITY AND IMPROVED COMBINATION OF DYE HUE AND DYE STABILITY EASTMAN KODAK COMPANY 2002-09-24 US disclosed
EP-0953871-B1 Photographic element containing yellow dye-forming photographic coupler EASTMAN KODAK CO (US) 2002-06-26 EP disclosed
EP-0953875-B1 Photographic element containing yellow coupler EASTMAN KODAK CO (US) 2001-10-31 EP disclosed
EP-0953873-B1 Photographic element containing acylacetamido yellow dye-forming couplers EASTMAN KODAK CO (US) 2001-09-26 EP disclosed
EP-0953872-B1 Photographic element containing improved acylacetamido yellow dye-forming coupler EASTMAN KODAK CO (US) 2001-08-22 EP disclosed
EP-0953872-A1 Photographic element containing improved acylacetamido yellow dye-forming coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0953870-A1 Photographic element containing acetamido DIR coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0953874-A1 Photographic element comprising yellow dye-forming photographic coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0953875-A1 Photographic element containing yellow coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0953871-A1 Photographic element containing yellow dye-forming photographic coupler EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0953873-A1 Photographic element containing acylacetamido yellow dye-forming couplers EASTMAN KODAK COMPANY (US) 1999-11-03 EP disclosed
EP-0751428-B1 Novel image-dye-forming couplers and photographic elements containing them KODAK LTD (GB) 1999-10-06 EP disclosed
US-5674667-A COLORFASTNESS; CONTRAST EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0751428-A1 Novel image-dye-forming couplers and photographic elements containing them KODAK LIMITED (GB) 1997-01-02 EP disclosed