Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.61 |
| ▸ | FABP6 | P51161 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | VNN1 | O95497 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054969 | 0.84 | FABP1 (0.79) | FABP1FABP6CXCR4CYP1A2CYP2C19 | |
| SCHEMBL29580004 | 0.83 | CXCR4 (0.74) | FABP1FABP6CXCR4CYP1A2CYP2C19 | |
| SCHEMBL5879525 | 0.83 | CXCR4 (0.74) | FABP1FABP6CXCR4CYP1A2CYP2C19 | |
| SCHEMBL2194571 | 0.77 | KDM5A (0.61) | CYP1A2CYP2C19CLK4CYP3A4CYP2D6 | |
| SCHEMBL2230559 | 0.77 | FABP1 (1.00) | FABP1FABP6CXCR4CYP1A2CYP2D6 | |
| SCHEMBL29664808 | 0.77 | FABP1 (1.00) | FABP1FABP6CXCR4CYP1A2CYP2D6 | |
| SCHEMBL23938199 | 0.77 | KDM4E (0.69) | FABP1FABP6CXCR4TSHRTP53 | |
| SCHEMBL11573094 | 0.77 | FABP1 (0.67) | FABP1FABP6CXCR4CYP1A2CYP2C19 | |
| SCHEMBL4718827 | 0.77 | FABP1 (0.67) | FABP1FABP6CXCR4ALDH1A1TSHR | |
| SCHEMBL6301782 | 0.77 | FABP1 (0.67) | FABP1FABP6CXCR4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651811-B | Isoxazole-containing pyridopyrimidone compound and preparation method and application thereof | 贵州大学 | 2022-06-07 | — | — | CN | disclosed |
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1268429-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001079172-A1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER Departament Brevets/Fontanes (FR) | 2001-10-25 | — | — | WO | disclosed |