Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14633632 | 1.00 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6297678 | 0.94 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5078630 | 0.93 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16786362 | 0.91 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30542215 | 0.91 | MEN1 (0.80) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1314972 | 0.91 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30542212 | 0.91 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7025692 | 0.89 | MAPT (0.73) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7033500 | 0.89 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6815786 | 0.89 | MAPT (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |