Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152811 | 0.94 | KMT2A (0.74) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL6302417 | 0.87 | MEN1 (0.89) | KMT2AMEN1POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11555611 | 0.84 | KMT2A (0.61) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL4690573 | 0.84 | MEN1 (0.79) | KMT2AMEN1POLBNPC1RAB9A | |
| Nitrobenzene SCHEMBL28122132 | 0.83 | MEN1 (0.62) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL20914562 | 0.82 | KMT2A (0.47) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL16367722 | 0.82 | KMT2A (0.76) | KMT2AMEN1POLBNPC1RAB9A | |
| Bicarbonate SCHEMBL1562172 | 0.82 | MAPK1 (0.68) | KMT2AMEN1POLBMAPTALDH1A1 | |
| Bicarbonate SCHEMBL27200925 | 0.82 | MAPK1 (0.68) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL28386018 | 0.82 | SMN1; SMN2 (0.61) | NPC1RAB9AMITFMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399044-B2 | Antimicrobial cationic polyamines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | ARG1, PARG, ARG2 | KMT2A 1557/4885MEN1 314/4885POLB 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.