Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004961 | 0.73 | ALDH2 (0.33) | ALDH2 | |
| SCHEMBL19584837 | 0.67 | F2RL1 (0.43) | ALDH2 | |
| SCHEMBL5987345 | 0.65 | ALDH2 (0.37) | ALDH2 | |
| SCHEMBL20844203 | 0.64 | — | — | |
| SCHEMBL6305348 | 0.63 | KCNA3 (0.39) | — | |
| SCHEMBL5040005 | 0.61 | ALDH2 (0.35) | ALDH2 | |
| SCHEMBL18876378 | 0.60 | ALDH2 (0.31) | ALDH2 | |
| SCHEMBL20793966 | 0.60 | ALDH2 (0.41) | ALDH2 | |
| SCHEMBL5986722 | 0.59 | KCNA3 (0.36) | — | |
| SCHEMBL13725473 | 0.59 | KCNA3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967201-B1 | for increasing activation of the 5-HT2C receptor in mammals; treatment of depression, obesity, bulimia, premenstrual syndrome, alcoholism, tobacco abuse, panic disorder | ELI LILLY AND COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| EP-1204654-B1 | BENZOFURYLPIPERAZINES: 5-HT2C SEROTONIN RECEPTOR AGONISTS | LILLY CO ELI (US) | 2003-07-23 | — | — | EP | disclosed |