Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831513 | 0.77 | GABRA1 (0.41) | KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL29615355 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL31511037 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL3276749 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1GAACA1 | |
| SCHEMBL15970052 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A1CYP1B1GAACA1 | |
| SCHEMBL9620 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CYP1A1CYP1B1KDM4EGAA | |
| SCHEMBL11164918 | 0.72 | TSHR (0.47) | ALDH1A1KDM4ETDP1CA1CA2 | |
| SCHEMBL1376849 | 0.72 | ALDH1A1 (0.55) | ALDH1A1CYP1A1CYP1B1KDM4EGAA | |
| SCHEMBL278798 | 0.71 | ALDH1A1 (0.61) | ALDH1A1CYP1A1CYP1B1TDP1CA1 | |
| SCHEMBL23162447 | 0.71 | ALDH1A1 (0.42) | ALDH1A1CYP1A1CYP1B1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2582 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199681-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2024-06-20 | — | — | US | claimed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| US-20230159450-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2023-05-25 | — | — | US | claimed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | claimed |
| EP-4146629-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | The Feinstein Institutes for Medical Research (US) | 2023-03-15 | — | — | EP | claimed |
| US-20230065387-A1 | SYNTHESIS OF TYROSINE KINASE INHIBITORS | ESCO ASTER PTE. LTD (SG) | 2023-03-02 | — | — | US | claimed |
| WO-2021226431-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2021-11-11 | — | — | WO | claimed |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | EVONETIX LTD. (GB) | 2021-11-02 | — | — | US | claimed |
| US-20210317161-A1 | A PROCESS FOR THE PREPARATION OF PASIREOTIDE | AURO PEPTIDES LTD (IN) | 2021-10-14 | — | — | US | claimed |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | SILICON VALLEY BANK | 2021-04-15 | — | — | US | claimed |
| EP-0700896-B1 | Photochemically cleavable agents able to chelate metals and compositions containing them | OREAL (FR) | 1996-11-06 | — | — | EP | claimed |
| US-5541206-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| EP-0443532-B1 | Temporary minimal protection synthesis of LH-RH analogs | SYNTEX INC (US) | 1994-06-29 | — | — | EP | claimed |
| US-5212288-A | Luteinizing hormone-releasing hormone antagonists | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | claimed |
| EP-0443532-A2 | Temporary minimal protection synthesis of LH-RH analogs | SYNTEX (U.S.A.) INC. (US) | 1991-08-28 | — | — | EP | claimed |
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| EP-0175290-A2 | Glycopeptides, method for their preparation and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1986-03-26 | — | — | EP | claimed |
| US-4215037-A | Partially protected human insulin-A-chain and process for its manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-07-29 | — | — | US | claimed |
| US-4012345-A | POLYPEPTIDES WHICH INHIBIT SECRETION OF GROWTH HORMONE SOMATOTROPIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-03-15 | — | — | US | claimed |
| US-3997517-A | PEPTIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-12-14 | — | — | US | claimed |