Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 18/20 | 0.61 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306300 | 0.76 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6307205 | 0.72 | GLP1R (0.70) | GLP1R | |
| SCHEMBL6306402 | 0.68 | GLP1R (0.62) | GLP1R | |
| SCHEMBL6305874 | 0.67 | GLP1R (0.53) | GLP1R | |
| SCHEMBL6303911 | 0.66 | GLP1R (0.56) | GLP1R | |
| SCHEMBL6304517 | 0.64 | GLP1R (0.56) | GLP1RTXNRD1 | |
| SCHEMBL6307038 | 0.64 | GLP1R (0.52) | GLP1R | |
| SCHEMBL6303718 | 0.63 | GLP1R (0.53) | GLP1R | |
| SCHEMBL12340156 | 0.62 | GLP1R (0.47) | GLP1R | |
| SCHEMBL31647125 | 0.62 | TXNRD1 (0.45) | GSRTXNRD1COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |