Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL27561694 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL10673544 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL29242729 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL29002739 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL10674387 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL1641106 | 1.00 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL323989 | 0.97 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| Azelaic Acid SCHEMBL7852023 | 0.97 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| Pentadecanoic Acid SCHEMBL17668919 | 0.97 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL15665264 | 0.97 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148863-B2 | DETERGENT COSMETIC COMPOSITIONS AND USE | OREAL (FR) | 2012-02-22 | — | — | EP | claimed |
| CN-1161093-C | Detergent cosmetic compositions and use | �ź㴫 | 2004-08-11 | — | — | CN | claimed |
| EP-1148863-B1 | DETERGENT COSMETIC COMPOSITIONS AND USE | OREAL (FR) | 2002-06-26 | — | — | EP | claimed |
| CN-1338920-A | Detergent cosmetic compositions and use | OREAL (FR) | 2002-03-06 | — | — | CN | claimed |
| CN-1161093-C | Detergent cosmetic compositions and use | �ź㴫 | 2004-08-11 | — | — | CN | disclosed |
| CN-1338920-A | Detergent cosmetic compositions and use | OREAL (FR) | 2002-03-06 | — | — | CN | disclosed |
| CN-1005060-B | Transparent polyvinyl chloride products and compositions | B·F古德里奇公司 | 1989-08-30 | — | — | CN | disclosed |
| US-4751118-A | CONTAINING AN ETHER STABILIZER | THE B. F. GOODRICH COMPANY (US) | 1988-06-14 | — | — | US | disclosed |
| CN-86105440-A | Transparent polyvinyl chloride products and compositions | — | 1987-05-27 | — | — | CN | disclosed |
| EP-0212648-A2 | Clear polyvinyl chloride articles and compositions | The B.F. GOODRICH Company (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4399075-A | Process for producing chlorinated phenoxytoluene derivatives | ASAHI CHEMICAL COMPANY, LIMITED (JP) | 1983-08-16 | — | — | US | disclosed |