Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630287 | 0.92 | KCNQ1 (0.39) | KCNQ1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL631050 | 0.91 | KCNQ1 (0.47) | KCNQ1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL630207 | 0.89 | KCNQ1 (0.54) | KCNQ1KMT2AGAATSHRFKBP1A | |
| SCHEMBL1382042 | 0.89 | KCNQ1 (0.54) | KCNQ1KMT2AGAATSHRFKBP1A | |
| SCHEMBL631253 | 0.85 | BDKRB1 (0.42) | KCNQ1POLB | |
| SCHEMBL630021 | 0.83 | KCNQ1 (0.44) | KCNQ1GAAALDH1A1TSHRPOLB | |
| SCHEMBL631193 | 0.83 | MEN1 (0.47) | KCNQ1KMT2APOLBFKBP1ASMN1; SMN2 | |
| SCHEMBL631041 | 0.82 | ELOVL6 (0.40) | KCNQ1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL629881 | 0.82 | KCNQ1 (0.46) | KCNQ1KMT2AGAATSHRFKBP1A | |
| SCHEMBL1381634 | 0.82 | KCNQ1 (0.46) | KCNQ1KMT2AGAATSHRFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |