Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631450 | 0.91 | KCNQ1 (0.36) | KCNQ1L3MBTL1KMT2AFKBP1AFKBP4 | |
| SCHEMBL1383737 | 0.90 | KCNQ1 (0.45) | ELOVL6KCNQ1TSHRL3MBTL1FKBP1A | |
| SCHEMBL630110 | 0.90 | KCNQ1 (0.45) | ELOVL6KCNQ1TSHRL3MBTL1FKBP1A | |
| SCHEMBL10287283 | 0.83 | ELOVL6 (0.41) | ELOVL6KCNQ1TSHRL3MBTL1KMT2A | |
| SCHEMBL630706 | 0.82 | KCNQ1 (0.46) | KCNQ1TSHRKMT2AFKBP1AFKBP4 | |
| SCHEMBL13225535 | 0.81 | ITGB1 (0.42) | ELOVL6KCNQ1FKBP1AFKBP4FKBP5 | |
| SCHEMBL631253 | 0.81 | BDKRB1 (0.42) | KCNQ1 | |
| SCHEMBL630003 | 0.81 | KCNQ1 (0.43) | KCNQ1TSHRFKBP1AFKBP4FKBP5 | |
| SCHEMBL631034 | 0.79 | KCNQ1 (0.44) | KCNQ1KMT2AF10ST14F2 | |
| SCHEMBL630287 | 0.79 | KCNQ1 (0.39) | KCNQ1TSHRKMT2AFKBP1AFKBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |