Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304103 | 0.88 | GLP1R (0.52) | GLP1RSMN1; SMN2 | |
| SCHEMBL6304349 | 0.86 | HSD17B10 (0.41) | GLP1RNPSR1 | |
| SCHEMBL6306880 | 0.85 | GLP1R (0.53) | GLP1R | |
| SCHEMBL6303981 | 0.82 | GLP1R (0.38) | GLP1R | |
| SCHEMBL6304237 | 0.74 | GLS (0.42) | GLP1RSMN1; SMN2MAPT | |
| SCHEMBL6304318 | 0.70 | GLP1R (0.40) | GLP1R | |
| SCHEMBL6303731 | 0.69 | L3MBTL1 (0.44) | GLP1RSMN1; SMN2NPSR1MAPT | |
| SCHEMBL6311372 | 0.68 | GLP1R (0.37) | GLP1R | |
| SCHEMBL6311321 | 0.68 | GLP1R (0.43) | GLP1RNPSR1 | |
| SCHEMBL6311001 | 0.67 | SMN1; SMN2 (0.41) | GLP1RSMN1; SMN2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |