Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038709 | 0.95 | ESR1 (0.43) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL11276357 | 0.88 | NPC1 (0.49) | NPC1RAB9APAX8JAK2TACR1 | |
| Hydrochloric Acid SCHEMBL11258931 | 0.87 | NPC1 (0.48) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL3286898 | 0.87 | NPC1 (0.48) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL3286896 | 0.87 | NPC1 (0.48) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL11041302 | 0.83 | TSHR (0.46) | TP53ESR1ALDH1A1GLATSHR | |
| SCHEMBL11039779 | 0.81 | CPA3 (0.39) | MME | |
| SCHEMBL11031009 | 0.80 | NPC1 (0.50) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL10782208 | 0.80 | NPC1 (0.50) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL11042266 | 0.80 | MME (0.39) | TP53MMEALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869788-B2 | DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1365023-A1 | DNA ENCODING NOVEL D-AMINOACYLASE AND PROCESS FOR PRODUCING D-AMINO ACID BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-20030207436-A1 | Dna encoding novel d-aminoacylase and process for producing d-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2003-11-06 | — | — | US | disclosed |