Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324872 | 0.86 | TSHR (0.48) | TSHRALDH1A1GLANR1H2NR1H3 | |
| SCHEMBL11042059 | 0.85 | TP53 (0.44) | ALDH1A1GLATP53MAPTHSD17B10 | |
| SCHEMBL2228190 | 0.84 | NR1H2 (0.38) | TSHRALDH1A1GLANR1H2NR1H3 | |
| SCHEMBL30401308 | 0.84 | TSHR (0.47) | TSHRALDH1A1GLANR1H2NR1H3 | |
| SCHEMBL11038709 | 0.84 | ESR1 (0.43) | TSHRALDH1A1GLATP53ESR1 | |
| SCHEMBL11039950 | 0.84 | S1PR1 (0.43) | TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6307359 | 0.83 | NPC1 (0.47) | TSHRALDH1A1GLATP53ESR1 | |
| SCHEMBL11719062 | 0.83 | ALDH1A1 (0.46) | TSHRALDH1A1GLANR1H2NR1H3 | |
| SCHEMBL5819570 | 0.81 | CPA3 (0.46) | ALDH1A1GLACPA3FOLH1KMT2A | |
| SCHEMBL1878620 | 0.81 | CYP1A2 (0.47) | TSHRALDH1A1GLANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |