Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758864 | 0.83 | IDO1 (0.47) | ALDH1A1TP53TSHRMCL1MEN1 | |
| SCHEMBL2089857 | 0.78 | HPGD (0.46) | ALDH1A1LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1758412 | 0.77 | LMNA (0.39) | LMNAGAAKMT2A | |
| SCHEMBL1758534 | 0.75 | GAA (0.50) | ALDH1A1LMNAGAATSHRMAPT | |
| SCHEMBL5542700 | 0.75 | MAPK1 (0.33) | ALDH1A1LMNAHPGDTSHRMCL1 | |
| SCHEMBL1268879 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTHPGDTSHR | |
| SCHEMBL6302331 | 0.72 | HSD17B10 (0.55) | ALDH1A1LMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28841644 | 0.72 | LMNA (0.40) | LMNANPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL27877503 | 0.71 | CYP2A6 (0.38) | SMN1; SMN2HTTGAAMEN1MAPT | |
| SCHEMBL29573961 | 0.70 | CA1 (0.53) | ALDH1A1LMNANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | claimed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |