Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367251 | 0.81 | MAPT (0.40) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL11040954 | 0.76 | BRD4 (0.41) | HTR2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8079031 | 0.73 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8079036 | 0.73 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8079034 | 0.73 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6590588 | 0.72 | HTR2C (0.44) | HTR2CHTR2AHTR2BALDH1A1DDB1 | |
| SCHEMBL2533981 | 0.70 | MAOB (0.38) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3083610 | 0.69 | HTR2C (0.42) | HTR2CHTR2AHTR2BALDH1A1DDB1 | |
| SCHEMBL9849476 | 0.69 | TSHR (0.45) | HTR2CHTR2AHTR2BALDH1A1DDB1 | |
| SCHEMBL11318483 | 0.68 | PBRM1 (0.39) | HTR2CHTR2AHTR2BALDH1A1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887700-B2 | Process for the enzymatic preparation of enantiopure 1, 3-dioxolan-4-one and 1,3-oxathiolan-5-one derivatives | Consortium für elektrochemische Industrie GmbH (DE) | 2005-05-03 | — | — | US | disclosed |