SCHEMBL28367251

SCHEMBL28367251

Cc1ccccc1C1OC(=O)CC(=O)O1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HPGD P15428 3/20 0.40
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
USP2 O75604 1/20 0.40
THRB P10828 1/20 0.40
HTR2C P28335 3/20 0.40
HTR2A P28223 1/20 0.40
HTR2B P41595 1/20 0.40
PBRM1 Q86U86 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6309846 0.81 HTR2C (0.41) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL28363323 0.78 MAP3K14 (0.37) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL31483441 0.77 ALDH1A1 (0.51) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL28363337 0.74 MTNR1A (0.45) MAPTALDH1A1HPGD
SCHEMBL25567626 0.73 TNKS2 (0.41) ALDH1A1MEN1KMT2APBRM1TNKS2
SCHEMBL9849476 0.72 TSHR (0.45) ALDH1A1DDB1CRBNHTR2CHTR2A
SCHEMBL6590588 0.71 HTR2C (0.44) ALDH1A1DDB1CRBNHTR2CHTR2A
SCHEMBL14012479 0.71 HTR2C (0.40) ALDH1A1MEN1KMT2ADDB1CRBN
SCHEMBL120709 0.71 MEN1 (0.48) MAPTALDH1A1MEN1KMT2A
SCHEMBL31483392 0.71 HTR2C (0.51) MAPTALDH1A1HPGDHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
CN-110799549-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2022-03-15 CN disclosed
CN-108473612-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2021-02-05 CN disclosed
CN-110997795-A High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2020-04-10 CN disclosed
CN-110799549-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2020-02-14 CN disclosed