Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079031 | 1.00 | MEN1 (0.45) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL8079034 | 1.00 | MEN1 (0.45) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL2533981 | 0.80 | MAOB (0.38) | MEN1KMT2ALMNACYP19A1MAOB | |
| SCHEMBL14612067 | 0.79 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19TSHRCYP2C9 | |
| SCHEMBL14578019 | 0.79 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19TSHRCYP2C9 | |
| SCHEMBL14612066 | 0.79 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19TSHRCYP2C9 | |
| SCHEMBL5406897 | 0.79 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19TSHRCYP2C9 | |
| SCHEMBL5432121 | 0.79 | MEN1 (0.41) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL120709 | 0.78 | MEN1 (0.48) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL6132937 | 0.78 | MEN1 (0.54) | MEN1KMT2ACYP2C19LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166074-A | Pharmaceutical compositions | NORSK HYDRO A.S. (NO) | 2000-12-26 | — | — | US | claimed |
| US-6166074-A | Pharmaceutical compositions | NORSK HYDRO A.S. (NO) | 2000-12-26 | — | — | US | disclosed |