SCHEMBL630993

SCHEMBL630993

CC(C)C[Si](CC(=O)O)(CC(=O)O)CC(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32
PGR P06401 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
CACNA2D2 Q9NY47 1/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828843 0.73 LMNA (0.40) CYP2D6CYP2C19ALDH1A1FFAR3
SCHEMBL5711158 0.69 FFAR3 (0.44) ALDH1A1TDP1FFAR3
SCHEMBL128808 0.69 FFAR3 (0.44) ALDH1A1TDP1FFAR3
SCHEMBL631982 0.67 FFAR3 (0.35) CYP2D6CYP2C19CACNA2D1CACNB3CACNA1C
SCHEMBL5711126 0.65 FFAR3 (0.41) ADRA1AALDH1A1TDP1FFAR3
3-Methylbutanoic Acid SCHEMBL467274 0.61 TDP1 (0.56) CYP2D6CYP2C19CACNA2D1CACNB3CACNA1C
SCHEMBL632284 0.61 FFAR3 (0.41) CYP2D6CYP2C19ADRA1AALDH1A1FFAR3
3-Methylbutanoic Acid SCHEMBL43436 0.61
SCHEMBL29065871 0.61 FFAR3 (0.41) CYP2D6CYP2C19ADRA1AALDH1A1FFAR3
3-Methylbutanoic Acid SCHEMBL1331498 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2419458-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD Dow Global Technologies LLC (US) 2012-02-22 EP disclosed
WO-2010120973-A1 PROCATALYST COMPOSITION WITH SILYL GLUTARATE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-21 WO disclosed