SCHEMBL6828843

SCHEMBL6828843

O=C(O)C[Si](CC(=O)O)(CC(=O)O)CC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
TSHR P16473 5/20 0.38
FFAR3 O14843 2/20 0.38
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
SLC22A6 Q4U2R8 2/20 0.35
CYP2D6 P10635 3/20 0.33
CYP2C19 P33261 1/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
HIF1A Q16665 1/20 0.33
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128808 0.79 FFAR3 (0.44) LMNALDHASRRALKBH5SUCNR1
SCHEMBL5711158 0.79 FFAR3 (0.44) LMNALDHASRRALKBH5SUCNR1
SCHEMBL5711126 0.75 FFAR3 (0.41) TSHRFFAR3OR51E2SLC22A6ALDH1A1
SCHEMBL630993 0.73 CYP2D6 (0.33) FFAR3CYP2D6CYP2C19ALDH1A1
SCHEMBL632284 0.69 FFAR3 (0.41) LMNALDHASRRALKBH5SUCNR1
SCHEMBL3420650 0.69
SCHEMBL7632130 0.69
SCHEMBL8415864 0.67
SCHEMBL3364899 0.64
SCHEMBL22464687 0.58 LMNA (0.75) LMNAALKBH5SUCNR1EGLN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040247271-A1 Hermetically sealed optical fibre with voids or holes, method of its production, and its use CRYSTAL FIBRE A/S (DK) 2004-12-09 US claimed
EP-1442323-A1 HERMETICALLY SEALED OPTICAL FIBRE WITH VOIDS OR HOLES, METHOD OF ITS PRODUCTION, AND ITS USE Crystal Fibre A/S (DK) 2004-08-04 EP claimed
WO-2003032039-A1 HERMETICALLY SEALED OPTICAL FIBRE WITH VOIDS OR HOLES, METHOD OF ITS PRODUCTION, AND ITS USE CRYSTAL FIBRE A/S (DK) 2003-04-17 WO claimed
EP-0146507-B1 METHOD FOR THE POLYMERISATION OF ETHYLENE AND FOR THE COPOLYMERISATION OF ETHYLENE WITH ALPHA-OLEFINS AND CATALYSTS FOR USE IN THE METHOD ENICHIMICA SECONDARIA S.p.A. (IT) 1988-03-02 EP claimed
EP-1442323-A1 HERMETICALLY SEALED OPTICAL FIBRE WITH VOIDS OR HOLES, METHOD OF ITS PRODUCTION, AND ITS USE Crystal Fibre A/S (DK) 2004-08-04 EP disclosed
WO-2003032039-A1 HERMETICALLY SEALED OPTICAL FIBRE WITH VOIDS OR HOLES, METHOD OF ITS PRODUCTION, AND ITS USE CRYSTAL FIBRE A/S (DK) 2003-04-17 WO disclosed
US-4803366-A Input screen scintillator for a radiological image intensifier tube and a method of manufacturing such a scintillator VIEUX GERARD (FR) 1989-02-07 US disclosed