SCHEMBL6310221

SCHEMBL6310221

CCn1c(C(F)(F)F)nn(-c2cc(NS(C)(=O)=O)c(C(N)=S)cc2F)c1=O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6310984 0.93 DHODH (0.38) DHODH
SCHEMBL6309814 0.88 DHODH (0.45) DHODH
SCHEMBL6310317 0.85 DHODH (0.38) DHODH
SCHEMBL7628626 0.83 DHODH (0.40) DHODH
SCHEMBL39236 0.83 DHODH (0.43) DHODH
SCHEMBL6310318 0.81 CTSK (0.36) DHODH
SCHEMBL8227965 0.79 DHODH (0.40) DHODH
SCHEMBL6315602 0.77 DHODH (0.38) DHODH
SCHEMBL6310856 0.76 DHODH (0.41) DHODH
Chlorthiamid SCHEMBL5268335 0.75 DHODH (0.42) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
US-6841517-B1 Selective herbicides on basis of N-aryl-triazoline(thi)ones BAYER AKTIENGESELLSCHAFT (DE) 2005-01-11 US disclosed
EP-1049376-B1 SELECTIVE HERBICIDES BASED ON N-ARYL- TRIAZOLINE(THI)ONS AND N-ARLYSULFONYLAMINO (THIO)CARBONYL- TRIAZOLINE(THI) ONS BAYER AG (DE) 2002-10-16 EP disclosed
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP disclosed
US-6297192-B1 MIXTURES OF HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-10-02 US disclosed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO disclosed