SCHEMBL6310318

SCHEMBL6310318

CCn1c(C(F)(F)F)nn(-c2cc(NS(C)(=O)=O)c(C#N)cc2F)c1=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.36
DHODH Q02127 15/20 0.34
PPOX P50336 1/20 0.34
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6307788 0.92 CTSK (0.36) CTSKDHODHAR
SCHEMBL6106477 0.88 DHODH (0.40) CTSKDHODHPPOX
SCHEMBL8829573 0.86 PPOX (0.35) DHODHPPOX
SCHEMBL6307815 0.84 PPOX (0.38) DHODHPPOX
SCHEMBL9053571 0.84 CTSK (0.41) CTSKDHODHAR
SCHEMBL9055831 0.83 DHODH (0.37) CTSKDHODHAR
SCHEMBL6504119 0.83 CTSK (0.35) CTSKDHODHPPOXAR
SCHEMBL6308458 0.82 PGR (0.40) CTSKDHODHAR
SCHEMBL9053504 0.81 CTSK (0.39) CTSKDHODHAR
SCHEMBL6104442 0.81 CTSK (0.39) CTSKDHODHAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
US-6841517-B1 Selective herbicides on basis of N-aryl-triazoline(thi)ones BAYER AKTIENGESELLSCHAFT (DE) 2005-01-11 US disclosed
EP-1049376-B1 SELECTIVE HERBICIDES BASED ON N-ARYL- TRIAZOLINE(THI)ONS AND N-ARLYSULFONYLAMINO (THIO)CARBONYL- TRIAZOLINE(THI) ONS BAYER AG (DE) 2002-10-16 EP disclosed
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP disclosed
US-6297192-B1 MIXTURES OF HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-10-02 US disclosed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO disclosed
EP-1049376-A1 SELECTIVE HERBICIDES BASED ON N-ARYL- TRIAZOLINE(THI)ONS AND N-ARLYSULFONYLAMINO (THIO)CARBONYL- TRIAZOLINE(THI) ONS Bayer Aktiengesellschaft (DE) 2000-11-08 EP disclosed
WO-1999037153-A1 SELECTIVE HERBICIDES BASED ON N-ARYL- TRIAZOLINE(THI)ONS AND N-ARLYSULFONYLAMINO (THIO)CARBONYL- TRIAZOLINE(THI) ONS BAYER AKTIENGESELLSCHAFT (DE) 1999-07-29 WO disclosed