Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311330 | 0.82 | SIGMAR1 (0.44) | HTR6HTR2CALDH1A1HTR2AKDM4E | |
| SCHEMBL6310625 | 0.78 | HTR2C (0.49) | HTR6HTR2CALDH1A1HTR2AKDM4E | |
| SCHEMBL6309715 | 0.71 | CYP2D6 (0.39) | HTR6HTR2CALDH1A1HTR2AKDM4E | |
| SCHEMBL11532274 | 0.67 | HTR2A (0.50) | HTR6HTR2CHTR2ACYP2D6HRH1 | |
| Hydrochloric Acid SCHEMBL11529408 | 0.66 | HTR2A (0.49) | HTR6HTR2CHTR2ACYP2D6HRH1 | |
| SCHEMBL11530208 | 0.62 | CYP1A2 (0.48) | HTR6MAPTRAD52CYP2D6CYP1A2 | |
| SCHEMBL4359561 | 0.61 | HTR2C (0.54) | HTR6HTR2CALDH1A1HTR2AKDM4E | |
| Hydrochloric Acid SCHEMBL11529493 | 0.61 | CYP1A2 (0.47) | HTR6KDM4EMAPTRAD52GAA | |
| SCHEMBL11392194 | 0.60 | CYP2D6 (0.45) | ALDH1A1HTR2AKDM4EMAPTHTT | |
| SCHEMBL27792651 | 0.60 | PTPN1 (0.46) | ALDH1A1KDM4EMAPTHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844344-B2 | Benzofuran derivatives | ELI LILLY AND COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030232833-A1 | Benzofuran derivatives | ELI LILLY AND COMPANY | 2003-12-18 | — | — | US | disclosed |
| EP-1246822-A1 | BENZOFURAN DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001046177-A1 | BENZOFURAN DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232833-A1 | Benzofuran derivatives | BRD1, BPTF, HTR1F | HTR6 38/4885HTR2C 52/4885ALDH1A1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.