Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 10/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311892 | 0.66 | HPGD (0.45) | GLP1RKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6305816 | 0.65 | GLP1R (0.73) | GLP1RALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6311017 | 0.65 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6311072 | 0.64 | GLP1R (0.53) | GLP1RKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6307427 | 0.62 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6311010 | 0.61 | GLP1R (0.77) | GLP1R | |
| SCHEMBL1425763 | 0.61 | GAA (0.52) | ALDH1A1KMT2AL3MBTL1TOP2A | |
| SCHEMBL6310949 | 0.61 | GLP1R (0.73) | GLP1R | |
| SCHEMBL6304275 | 0.60 | GLP1R (0.52) | GLP1RKDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11479242 | 0.59 | GAA (0.45) | ALDH1A1KMT2AL3MBTL1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |