Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576037 | 0.85 | PRMT6 (0.59) | PRMT6AGXTMAPTMBTD1TP53BP1 | |
| SCHEMBL30228501 | 0.84 | PRMT6 (0.62) | PRMT6AGXTMAPTMBTD1TP53BP1 | |
| SCHEMBL5790204 | 0.83 | AGXT (0.61) | PRMT6AGXTDRD3ADRA2C | |
| SCHEMBL7508176 | 0.82 | PRMT6 (0.47) | PRMT6AGXTMBTD1TP53BP1L3MBTL3 | |
| SCHEMBL4577359 | 0.81 | KHK (0.47) | PRMT6AGXTMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8200502 | 0.81 | AGXT (0.60) | PRMT6AGXTADRA2C | |
| SCHEMBL25497793 | 0.80 | L3MBTL3 (0.45) | PRMT6AGXTMBTD1TP53BP1L3MBTL3 | |
| SCHEMBL4577574 | 0.80 | CHRNA7 (0.56) | PRMT6AGXTMAPTSMN1; SMN2DRD2 | |
| SCHEMBL23844193 | 0.79 | L3MBTL3 (0.44) | PRMT6AGXTMBTD1TP53BP1L3MBTL3 | |
| SCHEMBL13005475 | 0.77 | HRH3 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |