⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165094 | 0.88 | NOS1 (0.53) | — | |
| SCHEMBL19287300 | 0.86 | NOS1 (0.51) | — | |
| SCHEMBL77889 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL68621 | 0.80 | — | — | |
| SCHEMBL307817 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7302305 | 0.80 | GABRA5 (0.52) | — | |
| Hydrochloric Acid SCHEMBL3450621 | 0.78 | NOS1 (0.56) | — | |
| SCHEMBL5911714 | 0.78 | — | — | |
| SCHEMBL9198409 | 0.78 | — | — | |
| SCHEMBL9602257 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-0032058-B1 | THIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4411900-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| EP-0032058-A1 | Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |