⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557928 | 0.67 | — | — | |
| SCHEMBL10623492 | 0.67 | — | — | |
| SCHEMBL2559278 | 0.65 | — | — | |
| SCHEMBL7679324 | 0.65 | — | — | |
| SCHEMBL13201155 | 0.62 | — | — | |
| SCHEMBL11324918 | 0.62 | CA1 (0.30) | — | |
| SCHEMBL11324914 | 0.62 | CA1 (0.30) | — | |
| SCHEMBL2485246 | 0.62 | — | — | |
| SCHEMBL13201161 | 0.62 | — | — | |
| SCHEMBL6311458 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105039489-A | Methods to manufacture 1,3-dioxolane nucleosides | UNIV EMORY | 2015-11-11 | — | — | CN | disclosed |
| CN-101044122-A | Process for preparing 1, 3-dioxolane nucleosides | UNIV EMORY (US) | 2007-09-26 | — | — | CN | disclosed |
| US-6887700-B2 | Process for the enzymatic preparation of enantiopure 1, 3-dioxolan-4-one and 1,3-oxathiolan-5-one derivatives | Consortium für elektrochemische Industrie GmbH (DE) | 2005-05-03 | — | — | US | disclosed |
| US-20030143698-A1 | Process for the enzymatic preparation of enantiopure 1, 3-dioxolan-4-one and 1,3-oxathiolan-5-one derivatives | WACKER CHEMIE AG (DE) | 2003-07-31 | — | — | US | disclosed |