⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211649 | 0.76 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL10623492 | 0.62 | — | — | |
| SCHEMBL3557928 | 0.62 | — | — | |
| SCHEMBL6310764 | 0.62 | — | — | |
| SCHEMBL2559278 | 0.60 | — | — | |
| SCHEMBL7679324 | 0.60 | — | — | |
| SCHEMBL23389134 | 0.58 | — | — | |
| SCHEMBL5406897 | 0.58 | CYP2C19 (0.46) | — | |
| SCHEMBL8079036 | 0.58 | MEN1 (0.45) | — | |
| SCHEMBL14578019 | 0.58 | CYP2C19 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147278-B1 | COMPOUND FOR TREATING BREAST CANCER AND PROGESTIN-DEPENDENT CONDITIONS | UNIV TENNESSEE RES FOUND (US) | 2020-02-12 | — | — | EP | disclosed |
| US-10300037-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190055192-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATOR AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2019-02-21 | — | — | US | disclosed |
| US-10010521-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180116994-A1 | SARMS AND METHOD OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2018-05-03 | — | — | US | disclosed |
| US-20180071242-A1 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2018-03-15 | — | — | US | disclosed |
| US-9844528-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-12-19 | — | — | US | disclosed |
| US-9730908-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-08-15 | — | — | US | disclosed |
| EP-3147278-A1 | COMPOUND FOR TREATING BREAST CANCER AND PROGESTIN-DEPENDENT CONDITIONS | University of Tennessee Research Foundation (US) | 2017-03-29 | — | — | EP | disclosed |
| US-20170014371-A1 | SARMS AND METHOD OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2017-01-19 | — | — | US | disclosed |
| EP-2054049-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-2038252-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20080076828-A1 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-27 | — | — | US | disclosed |
| US-20080076829-A1 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-27 | — | — | US | disclosed |
| US-20080057068-A1 | SARMS and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-06 | — | — | US | disclosed |
| WO-2008024456-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008008433-A2 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2008-01-17 | — | — | WO | disclosed |
| US-20070173546-A1 | Selective androgen receptor modulators and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2007-07-26 | — | — | US | disclosed |
| US-20070161608-A1 | Selective androgen receptor modulators for treating muscle wasting | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2007-07-12 | — | — | US | disclosed |
| US-20070123563-A1 | Selective androgen receptor modulators and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2007-05-31 | — | — | US | disclosed |