Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310797 | 1.00 | NPSR1 (0.49) | NPSR1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5770264 | 0.85 | ALDH1A1 (0.53) | NPSR1TSHRCYP2C19L3MBTL1POLB | |
| SCHEMBL5770247 | 0.85 | ALDH1A1 (0.53) | NPSR1TSHRCYP2C19L3MBTL1POLB | |
| SCHEMBL5770254 | 0.85 | ALDH1A1 (0.53) | NPSR1TSHRCYP2C19L3MBTL1POLB | |
| SCHEMBL6310767 | 0.84 | GLA (0.45) | NPSR1L3MBTL1POLBGAAMEN1 | |
| SCHEMBL6319715 | 0.84 | GLA (0.45) | NPSR1L3MBTL1POLBGAAMEN1 | |
| SCHEMBL6319712 | 0.84 | GLA (0.45) | NPSR1L3MBTL1POLBGAAMEN1 | |
| SCHEMBL4217833 | 0.84 | ALDH1A1 (0.47) | NPSR1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4217831 | 0.84 | ALDH1A1 (0.47) | NPSR1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1036337 | 0.79 | NPSR1 (0.43) | NPSR1TSHRCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | TACR2, TACR1, TAC3 | NPSR1 9/4885TSHR 975/4885CYP3A4 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.