Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.68 |
| ▸ | TYK2 | P29597 | 5/20 | 0.68 |
| ▸ | JAK1 | P23458 | 3/20 | 0.68 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420511 | 0.85 | JAK2 (0.56) | JAK2TYK2JAK1BRAFACVRL1 | |
| SCHEMBL24348414 | 0.85 | JAK2 (0.56) | JAK2TYK2JAK1BRAFACVRL1 | |
| SCHEMBL1977818 | 0.84 | TYK2 (0.68) | JAK2TYK2JAK1BRAFACVRL1 | |
| SCHEMBL18899922 | 0.83 | SMARCA2 (0.58) | JAK2TYK2JAK1RAB9APOLB | |
| SCHEMBL16311114 | 0.83 | JAK2 (0.53) | JAK2TYK2JAK1BRAFACVRL1 | |
| SCHEMBL13922914 | 0.83 | RAB9A (0.59) | RAB9APOLBMEN1KMT2ATSHR | |
| SCHEMBL8240613 | 0.83 | RAB9A (0.59) | RAB9APOLBMEN1KMT2ATSHR | |
| SCHEMBL3514246 | 0.82 | TYK2 (1.00) | JAK2TYK2JAK1 | |
| SCHEMBL18626344 | 0.81 | TSHR (0.54) | JAK2TYK2JAK1RAB9APOLB | |
| SCHEMBL16013758 | 0.81 | AR (0.59) | JAK2TYK2JAK1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3654929-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2020-05-27 | — | — | EP | claimed |
| EP-3236919-B1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | OREAL (FR) | 2019-10-16 | — | — | EP | claimed |
| US-10400186-B2 | Associative polymers for mist-control | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-03 | — | — | US | claimed |
| WO-2019016153-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2019-01-24 | — | — | WO | claimed |
| US-20180000712-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | L'OREAL (FR) | 2018-01-04 | — | — | US | claimed |
| EP-3236919-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | L'Oréal (FR) | 2017-11-01 | — | — | EP | claimed |
| WO-2016102489-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | L'OREAL (FR) | 2016-06-30 | — | — | WO | claimed |
| US-20130131095-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | SOCIETE L'OREAL S.A. (FR) | 2013-05-23 | — | — | US | claimed |
| EP-2419496-A1 | ASSOCIATIVE POLYMERS FOR MIST-CONTROL | California Institute of Technology (US) | 2012-02-22 | — | — | EP | claimed |
| EP-1352629-B1 | Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss | OREAL (FR) | 2011-06-22 | — | — | EP | claimed |
| WO-2010121270-A1 | ASSOCIATIVE POLYMERS FOR MIST-CONTROL | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-10-21 | — | — | WO | claimed |
| US-20100105741-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL (FR) | 2010-04-29 | — | — | US | claimed |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL | 2009-08-27 | — | — | US | claimed |
| US-20030223945-A1 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | SOCIETE L'OREAL S.A. (FR) | 2003-12-04 | — | — | US | claimed |
| US-10835468-B2 | Particular pyridinedicarboxylic acid derivative/antioxidant combination | L'OREAL (FR) | 2020-11-17 | — | — | US | disclosed |
| EP-3654929-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2020-05-27 | — | — | EP | disclosed |
| EP-3236919-B1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |
| US-7598278-B2 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | L'OREAL (FR) | 2009-10-06 | — | — | US | disclosed |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL | 2009-08-27 | — | — | US | disclosed |
| US-20030223945-A1 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | SOCIETE L'OREAL S.A. (FR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000712-A1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | GPX4, PRDX3, DPYD | JAK2 1218/4885TYK2 2167/4885JAK1 681/4885 |
| US-10835468-B2 | Particular pyridinedicarboxylic acid derivative/antioxidant combination | GPX4, PRDX3, DPYD | JAK2 1218/4885TYK2 2167/4885JAK1 681/4885 |
| US-20030223945-A1 | Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss | KRT18, AKR1C3, MC1R | JAK2 4556/4885TYK2 1813/4885JAK1 2341/4885 |
| US-20100105741-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | AKR1C3, MC1R, KRT18 | JAK2 4341/4885TYK2 1793/4885JAK1 2698/4885 |
| US-20130131095-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | AKR1C3, MC1R, KRT18 | JAK2 4341/4885TYK2 1793/4885JAK1 2698/4885 |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | AKR1C3, MC1R, KRT18 | JAK2 4341/4885TYK2 1793/4885JAK1 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.